OxyMon

Our most advanced and versatile fNIRS system


Publications using the OxyMon

Noninvasive measurement of regional cerebral blood flow and regional cerebral blood volume by near-infrared spectroscopy and indocyanine green dye dilution

To find a suitable method for measuring regional cerebral blood flow (rCBF) rapidly at the bedside is still a matter of investigation. The purpose here was to develop a noninvasive method for bedside rCBF measurement and to validate it with a …

Muscle oxygen consumption, determined by NIRS, in relation to external force and EMG

Local oxygen consumption in a muscle (V̇O2) can be determined by near infrared spectroscopy (NIRS). In principle it should be possible to use this measure to validate musculoskeletal models. However, the relationship between V̇O2 and external force, …

Cerebral oxygenation responses to standing in elderly patients with predominantly diastolic dysfunction

Patients with left ventricular dysfunction may have different orthostatic responses of blood pressure (BP) and cerebral oxygenation than healthy elderly subjects. We investigated orthostatic changes in systemic haemodynamic variables and cerebral …

Transcranial oximetry using fast near infrared spectroscopy can detect failure of collateral blood supply in humans

We tested the hypothesis that transcranial oximetry by fast scanning near infrared spectroscopy can detect local desaturation of hemoglobin in arterial vessels of cerebral circulation with impaired blood supply. A total of 74 near infrared …

Experimental verification of conditions for near infrared spectroscopy (NIRS)

Objectives: in vitro assessment of the reproducibility and the optimal separation and position of the optodes in continuous wave (CW-) NIRS measurement of local inhomogeneities in absorption and/or scattering. Methods: a CW- NIRS system (OXYMON) was …

RSI: oxygen consumption, blood flow, and reoxygenation in patients suffering RSI measured by noninvasive optical spectroscopy

Background: Repetitive Strain Injury (RSI) is a major problem in nowadays health care and creates high financial costs and personal distress. Average prevalence rates in the Netherlands vary from 20-40% of the working population. Insight into the …

Lateral frontal cortex oxygenation changes during translation and language switching revealed by non-invasive near-infrared multi-point measurements

The organisation of language in the brain of multilingual people remains controversial. Using a high temporal resolution 12-channel near-infrared continuous wave spectroscopy system, we have demonstrated that it is possible to monitor non-invasively, …

Muscle tissue oxygenation as a functional tool in the follow up of dermatomyositis [9]

Download PDFPDF Letter Muscle tissue oxygenation as a functional tool in the follow up of dermatomyositis Free M C P van Beekvelt1, R A Wevers1, B G M van Engelen1, W N J M Colier2 Author affiliations http://dx.doi.org/10.1136/jnnp.73.1.93 Request …

In vivo quantitative near-infrared spectroscopy in skeletal muscle during incremental isometric handgrip exercise

The aim of this study was to investigate the performance of in vivo quantitative near-infrared spectroscopy (NIRS) in skeletal muscle at various workloads. NIRS was used for the quantitative measurement of O2 consumption (mVO2) in the human flexor …

Simultaneous measurements of cerebral oxygenation changes during brain activation by near-infrared spectroscopy and functional magnetic resonance imaging in healthy young and elderly subjects

Near infrared spectroscopy (NIRS) and functional magnetic resonance imaging (fMRI) both allow non-invasive monitoring of cerebral cortical oxygenation responses to various stimuli. To compare these methods in elderly subjects and to determine the …

Effects of acetazolamide and furosemide on ventilation and cerebral blood volume in normocapnic and hypercapnic patients with COPD

Study objectives: Effects of chronic metabolic alkalosis and acidosis and their relation to central chemoregulation may differ between normocapnic and chronic hypercapnic patients with COPD. The relationship between responses of inspired ventilation …

Effects of furosemide versus captopril on postprandial and orthostatic blood pressure and on cerebral oxygenation in patients ≥70 years of age with heart failure

Elderly patients with heart failure are at risk of postprandial hypotension (PPH), orthostatic hypotension (OH), and concomitant cerebral oxygenation changes because of altered cardiovascular balance and the use of cardiovascular medications, such as …

Evaluation of brain toxicity following near infrared light exposure after indocyanine green dye injection

Indocyanine green (ICG) has excellent safety records and is widely used in medical diagnosis. Recently, a new method has been developed to estimate cerebral blood flow (CBF) using ICG in combination with near-infrared spectroscopy (NIRS). The new …

New methods for monitoring cerebral oxygenation and hemodynamics in patients with subarachnoid hemorrhage

Radiographic cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) do not reflect cerebral hemodynamics and oxygenation and may occur in the absence of clinical deficit and vice-versa. This report is to describe preliminary findings in further …

Quantitative near-infrared spectroscopy in human skeletal muscle: methodological issues and clinical application

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Nonuniform quadriceps O2 consumption revealed by near infrared multipoint measurements

Single location muscle monitoring does not reflect the heterogeneous activation of the muscle group(s) during a given exercise. Vastus lateralis and rectus femoris O2 consumption (VO2) was investigated, non-invasively, at rest and during maximal …

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The monitoring of a single muscle location does not reflect the heterogeneity of the muscle groups activation during exercise. In the past, measurements of oxygen consumption (VO2) at single muscle locations could be carried out non-invasively by …

Adipose tissue thickness affects in vivo quantitative near-IR spectroscopy in human skeletal muscle

The influence of adipose tissue thickness (ATT) on near-IR spectroscopy (NIRS) measurements in vivo was studied in the human flexor digitorum superficialis muscle at rest and during sustained isometric handgrip exercise. NIRS was used for the …

Can cerebral blood volume be measured reproducibly with an improved near infrared spectroscopy system?

In some circumstances, cerebral blood volume (CBV) can be used as a measure for cerebral blood flow. A new near infrared spectroscope was used for determining the reproducibility of CBV measurements assessed by the O2-method. Twenty-seven healthy …

Changes in cerebral oxygenation and blood flow during LBNP in spinal cord-injured individuals

Spinal cord-injured (SCI) individuals, having a sympathetic nervous system lesion, experience hypotension during sitting and standing. Surprisingly, they experience few syncopal events. This suggests adaptations in cerebrovascular regulation. …