Purpose: A self-paced maximal exercise protocol has demonstrated higher V˙ O 2 max values when compared against traditional tests. The aim was to compare physiological responses to this self-paced V˙ O 2 max protocol (SPV) in comparison to a …

Previous studies in children and older adults demonstrated faster oxygen uptake (VO2) kinetics in males compared with females, but young healthy adults have not been studied. We hypothesized that young men would have faster aerobic system dynamics in …

Background High-intensity interval training (HIT) improves exercise capacity in patients with chronic heart failure (CHF). Moreover, HIT was associated with improved resting cardiac function. However, the extent to which these improvements actually …

PURPOSE: Cardiovascular risk, predicted by peak O2 uptake (VO2peak), is increased in type 1 diabetes. We examined the contribution of central and peripheral mechanisms to VO2peak in physically active adults with type 1 diabetes. METHODS: Seven men …

We investigated whether leg and arm skeletal muscle, and cerebral deoxygenation, differ during incremental cycling exercise in men and women, and if women's lower capacity to deliver O2 affects tissue deoxygenation. Men (n=10) compared to women …

Objective: Analysis of cerebral and systemic hemodynamic consequences of ultrasound dilution cardiac output measurements. Design: Prospective, experimental piglet study. Setting: Animal laboratory. SUBJECTS: Nine piglets. INTERVENTIONS: Ultrasound …

Background and Purpose - Patients with orthostatic hypotension due to sympathetic failure become symptomatic when standing, although their capability to maintain cerebral blood flow is reported to be preserved. We tested the hypothesis that in …