Blood volume vs. deoxygenated NIRS signal: computational analysis of the effects muscle O 2 delivery and blood volume on the NIRS signals

Near-infrared spectroscopy (NIRS) signals quantify the oxygenated ($Δ$HbMbO 2 ) and deoxygenated ($Δ$HHbMb) heme group concentrations. $Δ$HHbMb has been preferred to $Δ$HbMbO 2 in evaluating skeletal muscle oxygen extraction because it is assumed to …