Effects of Aerobic Exercise on Cognitive and Cerebrovascular Function in Hypertensive Adults

The presence of hypertension in middle-age is a major risk factor for later-life development of cognitive and cardiovascular disease. Exercise is widely recommended to combat vascular and brain aging in hypertension. We sought to compare the effects …

The long and winding road: Effects of exercise intensity and type upon sustained attention

Aerobic exercise enhances the ability to sustain attention (peaking at moderate intensities) by stimulating noradrenergic activity, which affects the fronto-parietal attention network. Prior exercise studies examining attention have focused on the …

Acute effects of repeated cycling sprints in hypoxia induced by voluntary hypoventilation

Purpose: This study aimed to investigate the acute responses to repeated-sprint exercise (RSE) in hypoxia induced by voluntary hypoventilation at low lung volume (VHL). Methods: Nine well-trained subjects performed two sets of eight 6-s sprints on a …

The effects of skin and core tissue cooling on oxygenation of the vastus lateralis muscle during walking and running

Skin and core tissue cooling modulates skeletal muscle oxygenation at rest. Whether tissue cooling also influences the skeletal muscle deoxygenation response during exercise is unclear. We evaluated the effects of skin and core tissue cooling on …

Effects of high-altitude exposure on supraspinal fatigue and corticospinal excitability and inhibition

Purpose: While acute hypoxic exposure enhances exercise-induced central fatigue and can alter corticospinal excitability and inhibition, the effect of prolonged hypoxic exposure on these parameters remains to be clarified. We hypothesized that 5 days …

Cardiovascular and cerebral hemodynamics during exercise and recovery in obese individuals as a function of their fitness status

The aim of this study was to compare cardiovascular hemodynamics and cerebral oxygenation/perfusion (COP) during and after maximal incremental exercise in obese individuals according to their aerobic fitness versus age-matched healthy controls …

Oxygen delivery is not a limiting factor during post-exercise recovery in healthy young adults

Purpose It is still equivocal whether oxygen uptake recovery kinetics are limited by oxygen delivery and can be improved by supplementary oxygen. The present study aimed to investigate whether measurements of muscle and pulmonary oxygen uptake …

The influence of adipose tissue on spatially resolved near-infrared spectroscopy derived skeletal muscle oxygenation: The extent of the problem

Objective. Near-infrared spectroscopy (NIRS) measurements of tissue oxygen saturation (StO2) are useful for the assessment of skeletal muscle perfusion and function during exercise, however, they are influenced by overlying skin and adipose tissue. …

Extending the limits of force endurance: Stimulation of the motor or the frontal cortex?

Previous findings indicate that facilitation of primary motor cortex (PMC) activity using trans-cranial direct current stimulation (tDCS) could improve resistance to physical fatigue. However, studies have failed to consistently replicate these …

Impairments in microvascular function and skeletal muscle oxygenation in women with gestational diabetes mellitus: links to cardiovascular disease risk factors

Aims/hypothesis: Gestational diabetes mellitus (GDM) is a risk factor for the development of endothelial dysfunction and cardiovascular disease. However, in vivo microvascular endothelial function in GDM has not been investigated. This study aimed to …

Respiratory and locomotor muscle implications on the VO2 slow component and the VO2 excess in young trained cyclists

We investigated the impact of ramp and constant-load exercise on (i) respiratory muscle fatigue and locomotor muscle oxygenation, (ii) their relationship with the excess VO2 and VO2 slow component (SC). Fourteen male cyclists performed two tests to …

The Relationship between Peripheral Artery Disease Symptomatology and Ischemia

Background Fewer than half of individuals with peripheral artery disease (PAD) experience classic claudication, and the relationships between PAD typical or atypical symptom intensity, location, and description (classic or atypical) with ischemic …

Transcranial direct current stimulation improves isometric time to exhaustion of the knee extensors

Transcranial direct current stimulation (tDCS) can increase cortical excitability of a targeted brain area, which may affect endurance exercise performance. However, optimal electrode placement for tDCS remains unclear. We tested the effect of two …

Effect of hypoxia on cerebrovascular and cognitive function during moderate intensity exercise

Exercise in hypoxia places added demands on the brain and cerebrovasculature that can impact cognitive function. The purpose of this study was to investigate the effect of acute hypoxia on cerebrovascular hemodynamics, markers of neuro-steroidal …

Physiological characteristics of elite high-altitude climbers

Factors underlying the amplitude of exercise performance reduction at altitude and the development of high-altitude illnesses are not completely understood. To better describe these mechanisms, we assessed cardiorespiratory and tissue oxygenation …

Acute cocoa flavanol improves cerebral oxygenation without enhancing executive function at rest or after exercise

Acute exercise-induced improvements in cognitive function are accompanied by increased (cerebral) blood flow and increased brain-derived neurotrophic factor (BDNF) levels. Acute cocoa flavanol (CF) intake may improve cognitive function, cerebral …

Effects of continuous and intermittent exercise on executive function in children aged 8-10 years

Understanding the effects of acute exercise on executive function in prepubescent children may be important for the enhancement of school performance. This study assessed the effect of an acute bout of continuous (CONT) or intermittent (INT), …

Evaluation of muscle oxygenation by near infrared spectroscopy in patients with facioscapulohumeral muscular dystrophy

The purpose of the study was to determine muscle metabolism adaptation to exercise in facioscapulohumeral muscular dystrophy patients (FSHD) and to study the correlation with clinical functional status (6-min walk test).8 FSHD patients and 15 …

High-intensity Interval training enhances mobilization/functionality of endothelial progenitor cells and depressed shedding of vascular endothelial cells undergoing hypoxia

Purpose: Exercise training improves endothelium-dependent vasodilation, whereas hypoxic stress causes vascular endothelial dysfunction. Monocyte-derived endothelial progenitor cells (Mon-EPCs) contribute to vascular repair process by differentiating …

Improving peripheral and central vascular adjustments during exercise through a training program in adolescents with obesity

Objective: The effects of a training program (TP) on muscle microvascularization during exercise remained to be explored in adolescents with obesity. We hypothesized that a TP would lead to better microvascular adaptations to exercise in skeletal …