Objective: This double-blind, cross-over study examined in drug-näive hypertensives the effects of a single dose of dietary nitrate (beetroot juice, BRJ) on (a) office/ambulatory BP and arterial stiffness, (b) muscle microvascular function, and (c) …

The presence of hypertension in middle-age is a major risk factor for later-life development of cognitive and cardiovascular disease. Exercise is widely recommended to combat vascular and brain aging in hypertension. We sought to compare the effects …

Hypertension even when controlled, may accelerate arterial stiffening and impair the ability of the cerebrovasculature to increase blood flow to support neural activity, i.e., neurovascular coupling (NVC). Optimal NVC depends on continuous, …

Behavioral performance and hemodynamic changes in the prefrontal cortex (PFC) represent cerebrovascular reserve and may indicate functional deficits related to essential hypertension. Fifteen stage 1 hypertensive and normotensive males (19-55 years) …