Effects of acute nitric oxide precursor intake on peripheral and central fatigue during knee extensions in healthy men

New Findings: What is the central question of this study? What is the effect of acute NO precursor intake on vascular function, muscle and cerebral oxygenation and peripheral and central neuromuscular fatigue during knee-extension exercise? What is …

Neuromuscular evaluation of arm-cycling repeated sprints under hypoxia and/or blood flow restriction

Purpose: This study aimed to determine the effects of hypoxia and/or blood flow restriction (BFR) on an arm-cycling repeated sprint ability test (aRSA) and its impact on elbow flexor neuromuscular function. Methods: Fourteen volunteers performed an …

Effects of high-altitude exposure on supraspinal fatigue and corticospinal excitability and inhibition

Purpose: While acute hypoxic exposure enhances exercise-induced central fatigue and can alter corticospinal excitability and inhibition, the effect of prolonged hypoxic exposure on these parameters remains to be clarified. We hypothesized that 5 days …

Peripheral fatigue is not critically regulated during maximal, intermittent, dynamic leg extensions

Central motor drive to active muscles is believed to be reduced during numerous exercise tasks to prevent excessive peripheral fatigue development. The purpose of the present study was to use hypoxia to exacerbate physiological perturbations during a …