Oral nitrate supplementation differentially modulates cerebral artery blood velocity and prefrontal tissue oxygenation during 15 km time-trial cycling in normoxia but not in hypoxia

Background: Nitrate is a precursor of nitric oxide (NO), an important regulator of cerebral perfusion in normoxic and hypoxic conditions. Nitrate supplementation could be used to improve cerebral perfusion and oxygenation during exercise in hypoxia. …