Moderate dose of dietary nitrate improves skeletal muscle microvascular function in patients with peripheral artery disease

Peripheral artery disease (PAD) is an atherosclerotic disease characterized by compromised lower-extremity blood flow that impairs walking ability. We showed that a moderate dose of dietary nitrate in the form of beetroot juice (BRJ, 0.11 mmol/kg) …

Energy metabolism and muscle activation heterogeneity explain V̇O2$dotV_rmO_rm2$ slow component and muscle fatigue of cycling at different intensities

This study aimed to explain the slow component ( ) and muscle fatigue during cycling at different intensities. The muscle fatigue of 16 participants was determined through maximal isokinetic effort lasting 3 s during constant work rate bouts of …

Hypoxia Does Not Change Performance and Psychophysiological Responses During Repeated Cycling Sprints to Exhaustion With Short Exercise-to-Rest Ratio

Purpose : To compare the acute performance and psychophysiological responses of repeated cycling sprints to exhaustion with a short exercise-to-rest ratio (1:6), between different effort durations and inspired oxygen fractions. Methods : On …

Dietary Nitrate Supplementation Enhances Performance and Speeds Muscle Deoxyhaemoglobin Kinetics during an End-Sprint after Prolonged Moderate-Intensity Exercise

Short-term dietary nitrate (NO3−) supplementation has the potential to enhance performance during submaximal endurance, and short-duration, maximal-intensity exercise. However, it has yet to be determined whether NO3− supplementation before and …

Prefrontal cortex activation during incremental inspiratory loading in healthy participants

We aimed to investigate whether changes in prefrontal cortex (PFC) oxyhemoglobin (O2Hb) and deoxyhemoglobin (HHb) associates with inspiratory muscle effort during inspiratory threshold loading (ITL) in healthy participants. Participants performed an …

Peripheral microcirculatory alterations are associated with the severity of acute respiratory distress syndrome in COVID-19 patients admitted to intermediate respiratory and intensive care units

Abstract Background COVID-19 is primarily a respiratory disease; however, there is also evidence that it causes endothelial damage in the microvasculature of several organs. The aim of the present study is to characterize in vivo the microvascular …

Central and Peripheral Oxygen Distribution in Two Different Modes of Interval Training

In high-intensity interval training the interval duration can be adjusted to optimize training results in oxygen uptake, cardiac output, and local oxygen supply. This study aimed to compare these variables in two interval trainings (long intervals …

Acute effects of myofascial reorganization on trapezius muscle oxygenation in individuals with nonspecific neck pain

Background and purpose Nonspecific neck pain (NNP) is a common idiopathic disorder in the general population that affects the trapezius muscle (TM) and blood supply, thereby compromising the fascial system. Myofascial reorganization (MR) is a …

Performance Assessment of a Commercial Continuous-Wave Near-Infrared Spectroscopy Tissue Oximeter for Suitability for Use in an International, Multi-Center Clinical Trial

Despite the wide range of clinical and research applications, the reliability of the absolute oxygenation measurements of continuous wave near-infrared spectroscopy sensors is often questioned, partially due to issues of standardization. In this …

Effects of Acute Hypoxia on Psycho-Physiological Response and Muscle Oxygenation during Incremental Running Exercise

The objective of this study was to compare and evaluate the effectiveness of three protocols of intermittent exposure to simulated altitude (hypobaric hypoxia). This was done in order to determine the shortest protocol in which hematological changes …

Effects of high flow nasal cannula on exercise endurance in patients with chronic obstructive pulmonary disease

Background: Ventilation limitation has a significant adverse effects on cardiovascular function and tissue oxygenation during exercise in patients with chronic obstructive pulmonary disease (COPD). High flow nasal cannula (HFNC) improve ventilation …

Effects of Transcranial Direct Current Stimulation on Cycling Time Trial Performance and Prefrontal Cortex Activation

Background:Transcranial direct current stimulation (tDCS) is a neuromodulatory tech-nique that delivers low levels of a constant current via scalp electrodes to specificallytargeted areas of the brain. The effects of tDCS on whole-body exercise …

Non-invasive assessment of ribcage inspiratory muscle fatigue during two endurance tests in healthy subjects

Introduction: Fatigue is defined as a loss in the capacity for developing force and/or velocity of a muscle which is reversible by rest. The aim was to evaluate non-invasively the fatigue and recovery of the inspiratory ribcage muscles during two …