OxyMon

Our most advanced and versatile fNIRS system


Publications using the OxyMon

Blood volume vs. deoxygenated NIRS signal: computational analysis of the effects muscle O 2 delivery and blood volume on the NIRS signals

Near-infrared spectroscopy (NIRS) signals quantify the oxygenated ($Δ$HbMbO 2 ) and deoxygenated ($Δ$HHbMb) heme group concentrations. $Δ$HHbMb has been preferred to $Δ$HbMbO 2 in evaluating skeletal muscle oxygen extraction because it is assumed to …

Effects of graded hypoxia during exhaustive intermittent cycling on subsequent exercise performance and neuromuscular responses

This study examined the effect of graded hypoxia during exhaustive intermittent cycling on subsequent exercise performance and neuromuscular fatigue characteristics in normoxia. Fifteen well-trained cyclists performed an exhaustive intermittent …

Supplemental Watermelon Juice Attenuates Acute Hyperglycemia-Induced Macro-and Microvascular Dysfunction in Healthy Adults

Background Acute hyperglycemia reduces NO bioavailability and causes macro- and microvascular dysfunction. Watermelon juice (WMJ) is a natural source of the amino acid citrulline, which is metabolized to form arginine for the NO cycle and may improve …

The Role of Deconditioning in the End-Stage Renal Disease Myopathy: Physical Exercise Improves Altered Resting Muscle Oxygen Consumption

Background: Skeletal muscle dysfunction and poor exercise tolerance are hallmarks of end-stage renal disease (ESRD). Noninvasively measured (near-infrared spectroscopy, NIRS) resting muscle oxygen consumption (rmVO2) is a biomarker of muscle …

A randomized placebo-control trial of the acute effects of oxygen supplementation on exercise hemodynamics, autonomic modulation, and brain oxygenation in patients with pulmonary hypertension

Background: The integrative physiological effects of O2 treatment on patients with pulmonary hypertension (PH) during exercise, have not been fully investigated. We simultaneously evaluated, for the first time, the effect of oxygen supplementation on …

A randomized sham-controlled trial on the effect of continuous positive airway pressure treatment on gait control in severe obstructive sleep apnea patients

To determine the effect of continuous positive airway pressure (CPAP), the gold standard treatment for obstructive sleep apnea syndrome (OSAS), on gait control in severe OSAS patients. We conducted a randomized, double-blind, parallel-group, …

Diminished prefrontal cortex activation in patients with binge eating disorder associates with trait impulsivity and improves after impulsivity-focused treatment based on a randomized controlled IMPULS trial

Background Behavioral and cognitive control are vital for healthy eating behavior. Patients with binge eating disorder (BED) suffer under recurrent binge eating episodes accompanied by subjective loss of control that results, among other factors, …

Muscle mitochondrial capacity in high‐ and low‐fitness females using near‐infrared spectroscopy

The recovery of muscle oxygen consumption (m (Formula presented.) O2) after exercise measured using near-infrared spectroscopy (NIRS) provides a measure of skeletal muscle mitochondrial capacity. Nevertheless, due to sex differences in factors that …

Exertional Desaturation in Idiopathic Pulmonary Fibrosis: The Role of Oxygen Supplementation in Modifying Cerebral-Skeletal Muscle Oxygenation and Systemic Hemodynamics

Background: In patients with idiopathic pulmonary fibrosis (IPF) with isolated exertional desaturation, there are limited data regarding the effectiveness of oxygen supplementation during exercise training; the underlying mechanisms that contribute …

fNIRS signal quality estimation by means of a machine learning algorithm trained on morphological and temporal features

Functional near infrared spectroscopy (fNIRS) is used for brain hemodynamic assessment. Cortical hemodynamics are reliably estimated when the recorded signal has a sufficient quality. This is acquired when fNIRS optodes have proper scalp coupling. A …

Multiple-day high-dose beetroot juice supplementation does not improve pulmonary or muscle deoxygenation kinetics of well-trained cyclists in normoxia and hypoxia

Dietary nitrate (NO3 -) supplementation via beetroot juice (BR) has been reported to lower oxygen cost (i.e., increased exercise efficiency) and speed up oxygen uptake (VO2) kinetics in untrained and moderately trained individuals, particularly …

Reduced post‐exercise muscle microvascular perfusion with compression is offset by increased muscle oxygen extraction: Assessment by contrast‐enhanced ultrasound

The microvasculature is important for both health and exercise tolerance in a range of populations. However, methodological limitations have meant changes in micro- vascular blood flow are rarely assessed in humans during interventions designed to …

A systematic Review of Studies that Used NIRS to Measure Neural Activation During Emotion Processing in Healthy Individuals

Functional neuroimaging provides an avenue for earlier diagnosis and tailored treatment of psychological disorders characterized by emotional impairment. Near-infrared spectroscopy offers ecological advantages compared to other neuroimaging …

A Functional Near-Infrared Spectroscopy Examination of the Neural Correlates of Cognitive Shifting in Dimensional Change Card Sort Task

This study aims to examine the neural correlates of cognitive shifting during the Dimensional Change Card Sort Task (DCCS) task with functional near-infrared spectroscopy. Altogether 49 children completed the DCCS tasks, and 25 children (Mage = …

Circulating biomarkers of nitric oxide bioactivity and impaired muscle vasoreactivity to exercise in adults with uncomplicated type 1 diabetes

Aims/hypothesis: Early compromised endothelial function challenges the ability of individuals with type 1 diabetes to perform normal physical exercise. The exact mechanisms underlying this vascular limitation remain unknown, but may involve either …

Mitochondrial Capacity and Muscle Endurance in Individuals with Parkinson's Disease

Introduction: Parkinson's disease (PD) is associated with loss of motor control and difficulty exercising. This study measured skeletal muscle mitochondrial capacity and endurance in individuals with and without PD using novel non-invasive methods. …

Thirst perception exacerbates objective mental fatigue

Thirst is represented within the anterior cingulate and insular cortices, and may share some common neuroanatomical structures that are implicated with the regulation of mental fatigue. This novel study investigated whether thirst might modulate the …

The Effect of Spinal Manipulation on the Electrophysiological and Metabolic Properties of the Tibialis Anterior Muscle

There is growing evidence showing that spinal manipulation increases muscle strength in healthy individuals as well as in people with some musculoskeletal and neurological disorders. However, the underlying mechanism by which spinal manipulation …

Investigation of Functional Connectivity During Working Memory Task and Hemispheric Lateralization in Left- and Right- Handers Measured by fNIRS

Working memory is regarded as a cognitive system with limited capacity, which is responsible for saving, manipulating, and remembering online information. The cognitive functions of the brain, such as language, understanding, planning, reasoning, and …

Signal quality index: an algorithm for quantitative assessment of functional near infrared spectroscopy signal quality

We propose the signal quality index (SQI) algorithm as a novel tool for quantitatively assessing the functional near infrared spectroscopy (fNIRS) signal quality in a numeric scale from 1 (very low quality) to 5 (very high quality). The algorithm …