OxyMon

Our most advanced and versatile fNIRS system


Publications using the OxyMon

Focal Hemodynamic Responses in the Stimulated Hemisphere During High-Definition Transcranial Direct Current Stimulation

Objective: High-definition transcranial direct current stimulation (HD-tDCS) using a 4 × 1 electrode montage has been previously shown using modeling and physiological studies to constrain the electric field within the spatial extent of the …

Intercostal muscle oxygenation during expiratory load breathing

Aims: Objectives During acute bronchial obstruction, the work of breathing increases, while a reduction in perfusion of respiratory muscles due to hyperinflation and/or mechanical constraints may impair the contraction. To test this hypothesis, …

Investigation of confounding factors in measuring tissue saturation with NIRS spatially resolved spectroscopy

Performing absolute measurements of tissue saturation of the brain with near-infrared spectroscopy (NIRS) is a clinically desirable brain monitoring tool. Tissue oxygenation index (TOI) is an indicator of absolute tissue mixed arterial and venous …

Short-term preconditioning with blood flow restricted exercise preserves quadriceps muscle endurance in patients after anterior cruciate ligament reconstruction

Surgical ACL reconstruction performed with a tourniquet induces compression and ischemic stress of the quadriceps femoris (QF) muscle which can accelerate postoperative weakness. Given that low-load blood flow restricted (BFR) exercise is potent in …

The Benefits of Neuromuscular Electrical Stimulation in the Muscular and Functional Capacity of Patients With Liver Cirrhosis: Protocol for a Randomized Clinical Trial

Cirrhosis causes systemic and metabolic changes that culminate in various complications, such as compromised pulmonary function, ascites, hepatic encephalopathy, weight loss, and muscle weakness with significant physical function limitations. Our aim …

The effects of a 7-day water aerobics exercise intervention on the cerebral hyperemic response to a cognitive task in individuals with Multiple Sclerosis

Introduction: Widespread cerebral hypometabolism occurs in multiple sclerosis (MS) which can result in cognitive dysfunction. The purpose of this study was to determine the effects of a 7-day water aerobics exercise intervention on the cerebral …

The long and winding road: Effects of exercise intensity and type upon sustained attention

Aerobic exercise enhances the ability to sustain attention (peaking at moderate intensities) by stimulating noradrenergic activity, which affects the fronto-parietal attention network. Prior exercise studies examining attention have focused on the …

Assessing muscular oxygenation during incremental exercise using near-infrared spectroscopy: Comparison of three different methods

Using continuous-wave near-infrared spectroscopy (NIRS), this study compared three different methods, namely the slope method (SM), the amplitude method (AM), and the area under the curve (AUC) method to determine the variations of intramuscular …

The effectiveness of Robot-Assisted Gait Training versus conventional therapy on mobility in severely disabled progressIve MultiplE sclerosis patients (RAGTIME): Study protocol for a randomized controlled trial

Background: Gait and mobility impairments affect the quality of life (QoL) of patients with progressive multiple sclerosis (MS). Robot-assisted gait training (RAGT) is an effective rehabilitative treatment but evidence of its superiority compared to …

The reliability and minimal detectable change of the cardiovascular response and self-selected exercise intensity during forward and backward treadmill exercise in individuals with Parkinson disease

OBJECTIVE This study examined test-retest relative (intraclass correlation coefficient) and absolute (minimum detectable change) reliabilities for heart rate, blood pressure, rate of perceived exertion, and the cerebral oxygen response during both …

A comparison of head motion and prefrontal haemodynamics during upright and recumbent cycling exercise

The aim of this observational study was to compare head motion and prefrontal haemodynamics during exercise using three commercial cycling ergometers. Participants (n = 12) completed an incremental exercise test to exhaustion during upright, …

Dynamics of the human brain network revealed by time-frequency effective connectivity in fNIRS

© 2017 Optical Society of America. Functional near infrared spectroscopy (fNIRS) is a promising neuroimaging method for investigating networks of cortical regions over time. We propose a directed effective connectivity method (TPDC) allowing the …

Cerebral hemodynamics and executive function during exercise and recovery in normobaric hypoxia

Hypoxia and exercise each exhibit opposing effects on executive function, and the mechanisms for this are not entirely clear. This study examined the influence of cerebral oxygenation and perfusion on executive function during exercise and recovery …

Fatigability, oxygen uptake kinetics and muscle deoxygenation in incomplete spinal cord injury during treadmill walking

Purpose: The purpose of the present study was to characterize hypothesized relationships among fatigability and cardiorespiratory fitness in individuals with chronic motor-incomplete SCI (iSCI) during treadmill walking. The theoretical framework was …

Mitochondrial capacity, muscle endurance, and low energy in friedreich ataxia

Introduction: In this study we noninvasively evaluated skeletal muscle mitochondrial capacity, muscle-specific endurance, and energy/fatigue feelings in persons with Friedreich ataxia (FRDA) and able-bodied controls (AB). Methods: Forearm …

The effects of skin and core tissue cooling on oxygenation of the vastus lateralis muscle during walking and running

Skin and core tissue cooling modulates skeletal muscle oxygenation at rest. Whether tissue cooling also influences the skeletal muscle deoxygenation response during exercise is unclear. We evaluated the effects of skin and core tissue cooling on …

A Toe Flexion NIRS assisted Test for Rapid Assessment of Foot Perfusion in Peripheral Arterial Disease: Feasibility, Validity, and Diagnostic Accuracy

Objectives Feasibility, validity, and diagnostic accuracy of a non-invasive dynamic ambulatory test were assessed with near infrared spectroscopy (NIRS) evaluating foot perfusion in peripheral arterial disease (PAD). Methods This was a prospective …

Effects of high-altitude exposure on supraspinal fatigue and corticospinal excitability and inhibition

Purpose: While acute hypoxic exposure enhances exercise-induced central fatigue and can alter corticospinal excitability and inhibition, the effect of prolonged hypoxic exposure on these parameters remains to be clarified. We hypothesized that 5 days …

The venous–arterial difference in CO2 should be interpreted with caution in case of respiratory alkalosis in healthy volunteers

The venous–arterial difference in CO2 ($Δ$CO2) has been proposed as an index of the adequacy of tissue perfusion in shock states. We hypothesized that the variation in PaCO2 (hyper- or hypocapnia) could impact $Δ$CO2, partly through microcirculation …

Cardiovascular and cerebral hemodynamics during exercise and recovery in obese individuals as a function of their fitness status

The aim of this study was to compare cardiovascular hemodynamics and cerebral oxygenation/perfusion (COP) during and after maximal incremental exercise in obese individuals according to their aerobic fitness versus age-matched healthy controls …