Age-Related Changes in Skeletal Muscle Oxygen Utilization

The cardiovascular and skeletal muscle systems are intrinsically interconnected, sharing the goal of delivering oxygen to metabolically active tissue. Deficiencies within those systems that affect oxygen delivery to working tissues are a hallmark of …

Agreement between multiparametric MRI (PIVOT), Doppler ultrasound, and near-infrared spectroscopy-based assessments of skeletal muscle oxygenation and perfusion

Skeletal muscle perfusion and oxygenation are commonly evaluated using Doppler ultrasound and near-infrared spectroscopy (NIRS) techniques. However, a recently developed magnetic resonance imaging (MRI) sequence, termed PIVOT, permits the …

Astragalosides Supplementation Enhances Intrinsic Muscle Repair Capacity Following Eccentric Exercise-Induced Injury

Astragalosides have been shown to enhance endurance exercise capacity in vivo and promote muscular hypertrophy in vitro. However, it remains unknown whether astragalosides supplementation can alter inflammatory response and enhance muscle recovery …

Effect of moderate and Severe Hypoxic exposure coupled with fatigue on psychomotor vigilance testing, muscle tissue oxygenation, and muscular performance

Purpose The purpose of this study is to examine the effects of fatigue on muscular performance, oxygenation saturation, and cognition following acute hypoxic exposure at Normoxia, Moderate Hypoxia (MH), and Severe Hypoxia (SH). Methods Twelve males …

Effects of Personalized Cognitive Training with the Machine Learning Algorithm on Neural Efficiency in Healthy Younger Adults

To date, neural efficiency, an ability to economically utilize mental resources, has not been investigated after cognitive training. The purpose of this study was to provide customized cognitive training and confirm its effect on neural efficiency by …

Experimental study of transcranial pulsed current stimulation on relieving athlete’s mental fatigue

Objective To explore the effect of independently developed transcranial pulsed current stimulation (tPCS) on alleviating athlete’s mental fatigue. Methods A total of 60 college athletes were randomly divided into the active stimulation group …

Firefighter pre-frontal cortex oxygenation and hemodynamics during rapid heat stress

This study evaluated the impact of rapid heat stress on prefrontal cortex (PFC) oxygenation and hemodynamics. Previous work has demonstrated that heat stress affects cerebral oxygenation and hemodynamics. Fourteen male subjects performed a graded …

Functional Connectivity Across Dorsal And Ventral Attention Networks In Response To Task Difficulty And Experimental Pain

The dorsal and ventral attention networks (DAN & VAN) provide a framework for studying attentional modulation of pain. It has been argued that cognitive demand distracts attention from painful stimuli via top-down reinforcement of task goals (DAN), …

History of Brain Injury Alters Cerebral Haemodynamic Oscillations with Cardiac Influence

(1) Background: Cerebral autoregulation is altered during acute mild traumatic brain injury, or concussion. However, it is unknown how a history of concussion can impact cerebral haemodynamic activity during a task that elicits an autoregulatory …

Independent effects of acute normobaric hypoxia and hypobaric hypoxia on human physiology

Abstract The purpose of this study was to examine the effects of acute normobaric (NH, decreased FiO 2 ) and hypobaric (HH, 4200 m ascent) hypoxia exposures compared to sea level (normobaric normoxia, NN). Tissue oxygenation, cardiovascular, and …

Load-Dependent Prefrontal Cortex Activation Assessed by Continuous-Wave Near-Infrared Spectroscopy during Two Executive Tasks with Three Cognitive Loads in Young Adults

The present study examined the evolution of the behavioral performance, subjectively perceived difficulty, and hemodynamic activity of the prefrontal cortex as a function of cognitive load during two different cognitive tasks tapping executive …

Neural activation in the prefrontal cortex during the digital clock drawing test measured with functional near-infrared spectroscopy in early stage Parkinson's disease

Introduction The clock drawing test (CDT) is a neuropsychological test for the screening of global cognitive functioning. The test requires use of multiple cognitive domains including executive functions, visuospatial abilities and semantic memory …

Non-invasive near-infrared spectroscopy assessment of the spinal neurovascular response in a patient with transverse myelitis: a case report

Abstract Background Transverse myelitis (TM) is characterized by acute development of motor, sensory and autonomic dysfunctions due to horizontally diffused inflammation in one or more segments of the spinal cord in the absence of a compressive …

Peripheral muscle oxygenation and symptoms of stress in adolescents with and without temporomandibular disorder

Objective: To compare peripheral muscle oxygenation levels and the prevalence of psychological stress in adolescents with and without temporomandibular disorder (TMD). Methods: A cross-sectional study was performed with adolescents submitted into …

Physically active men present a healthier cardiometabolic profile in response to a balanced meal compared to inactive men

Purpose: Post-meal cardiometabolic responses are critical for health, and may be influenced by physical activity. The objective of this study was to investigate the effect of habitual physical activity level on the metabolic, autonomic nervous system …

Treadmill training in Parkinson’s disease is underpinned by the interregional connectivity in cortical-subcortical network

Abstract Treadmill training (TT) has been extensively used as an intervention to improve gait and mobility in patients with Parkinson’s disease (PD). Regional and global effects on brain activity could be induced through TT. Training effects can lead …

Altered psychobiological reactivity but no impairment of emotion recognition following stress in adolescents with non-suicidal self-injury

Abstract Impairments in both stress regulation and emotion recognition have been associated with borderline personality disorder (BPD) and non-suicidal self-injury (NSSI). Although it has been proposed that emotion recognition deficits particularly …

Assessing functional sympatholysis during rhythmic handgrip using Doppler ultrasound and near-infrared spectroscopy: sex differences and test-retest reliability

The effects of sympathetic activity on vasoconstriction are dampened in active skeletal muscle during exercise, a phenomenon termed functional sympatholysis. Limited work has examined the influence of sex on the magnitude of sympatholysis or the …

Functional near-infrared spectroscopy imaging of the prefrontal cortex during a naturalistic comedy movie

Naturalistic stimulation (i.e., movies and auditory narratives of some minutes’ length) has been a powerful approach to bringing more real-life experiences into laboratory experiments. Data-driven, intersubject correlation (ISC) analysis permits …

Functional NIRS to detect covert consciousness in neurocritical patients

Objective This pilot study assesses the feasibility to detect covert consciousness in clinically unresponsive patients by means of functional near infrared spectroscopy (fNIRS) in a real intensive care unit setting. We aimed to verify if the …