Dietary nitrate improves muscle microvascular reactivity and lowers blood pressure at rest and during isometric exercise in untreated hypertensives

Objective: This double-blind, cross-over study examined in drug-näive hypertensives the effects of a single dose of dietary nitrate (beetroot juice, BRJ) on (a) office/ambulatory BP and arterial stiffness, (b) muscle microvascular function, and (c) …

A single dose of beetroot juice improves endothelial function but not tissue oxygenation in pregnant women: A randomised clinical trial

Beetroot juice (BJ) consumption has been associated with improved cardiovascular health owing to an increase in NO bioconversion. This study evaluates the effect of BJ consumption on macrovascular endothelial function (flow-mediated dilation (FMD)) …

The venous–arterial difference in CO2 should be interpreted with caution in case of respiratory alkalosis in healthy volunteers

The venous–arterial difference in CO2 ($Δ$CO2) has been proposed as an index of the adequacy of tissue perfusion in shock states. We hypothesized that the variation in PaCO2 (hyper- or hypocapnia) could impact $Δ$CO2, partly through microcirculation …

Vibration-related extrusion of capillary blood from the calf musculature depends upon directions of vibration of the leg and of the gravity vector

Purpose: In this study, we investigated the effects of vibration of the whole lower leg on the content and the oxygenation of hemoglobin in the unloaded relaxed lateral gastrocnemius muscle. Vibration was applied orthogonal to and in parallel with …