OxyMon

Our most advanced and versatile fNIRS system


Publications using the OxyMon

Influence of cerebral and muscle oxygenation on repeated-sprint ability

The study examined the influence of cerebral (prefrontal cortex) and muscle (vastus lateralis) oxygenation on the ability to perform repeated, cycling sprints. Thirteen team-sport athletes performed ten, 10-s sprints (with 30 s of rest) under …

Quantification of CMRO 2 without hypercapnia using simultaneous near-infrared spectroscopy and fMRI measurements

Estimation of the cerebral metabolic rate of oxygen (CMRO 2) and cerebral blood flow (CBF) is important to investigate the neurovascular coupling and physiological components in blood oxygenation level-dependent (BOLD) signals quantitatively. …

Cerebral oxygenation decreases but does not impair performance during self-paced, strenuous exercise

Aim: The reduction in cerebral oxygenation (Cox) is associated with the cessation of exercise during constant work rate and incremental tests to exhaustion. Yet in exercises of this nature, ecological validity is limited due to work rate being either …

Do radio frequencies of medical instruments common in the operating room interfere with near-infrared spectroscopy signals?

Background:Medical and diagnostic applications of near infrared spectroscopy (NIRS) areincreasing, especially in operating rooms (OR). Since NIRS is anoptical technique, radio frequency (RF) interference from other instruments isunlikely to affect …

A prior bout of contractions speeds V̇o2 and blood flow on-kinetics and reduces the V̇o2 slow-component amplitude in canine skeletal muscle contracting in situ

It was the purpose of this study to examine the effect of a priming contractile bout on oxygen, uptake (V̇o2) on-kinetics in highly oxidative skeletal muscle. Canine gastrocnemii (n = 12) were stimulated via their sciatic nerves (8 V, 0.2-ms …

Application of ultrasound dilution technology for cardiac output measurement: Cerebral and systemic hemodynamic consequences in a juvenile animal model

Objective: Analysis of cerebral and systemic hemodynamic consequences of ultrasound dilution cardiac output measurements. Design: Prospective, experimental piglet study. Setting: Animal laboratory. SUBJECTS: Nine piglets. INTERVENTIONS: Ultrasound …

Cortical oxygen supply during postural hypotension is further decreased in Alzheimer's disease, but unrelated to cholinesterase-inhibitor use

Cerebrovascular function and structure of the cortical cerebral microvessels are profoundly altered in patients with Alzheimer's disease (AD). The functional hemodynamic consequences of such changes, however, remain essentially unknown. …

Reduction of oxygenation and blood flow in pedicled bowel segments in the rat and its consequences for anastomotic healing

Purpose: Experimental studies indicate that perioperative hypoperfusion impairs anastomotic healing. In bowel surgery, the part of bowel that will be anastomosed is often pedicled, leaving the blood supply dependent on the marginal artery only. …

Resting muscle oxygen consumption by near-infrared spectroscopy in peripheral arterial disease: A parameter to be considered in a clinical setting?

Resting muscle VO2 consumption (rmVO2) as measured by near-infrared spectroscopy (NIRS) has been poorly studied in peripheral arterial disease (PAD). We studied the feasibility of its assessment in a clinical setting, compared values from PAD and …

Role of skeletal muscles impairment and brain oxygenation in limiting oxidative metabolism during exercise after bed rest

"Central" and "peripheral" limitations to oxidative metabolism during exercise were evaluated in 10 young males following a 35-day horizontal bed rest (BR). Incremental exercise (IE) and moderate- and heavy-intensity constant-load exercises (CLE) …

Skeletal muscle metabolic recovery following submaximal exercise in chronic heart failure is limited more by O2 delivery than O2 utilization

CHF (chronic heart failure) is associated with a prolonged recovery of skeletal muscle energy stores following submaximal exercise, limiting the ability to perform repetitive daily activities. However, the pathophysiological background of this …

The effect of elbow angle and external moment on load sharing of elbow muscles

To study elbow muscle load sharing we investigated the effect of external flexion-extension (FE) and pronation-supination (PS) moments and elbow angle on muscle activation and oxygen consumption (V̇O2).Two data sets were obtained. First, (n=6) …

Effect of bladderbox alarms during venoarterial extracorporeal membrane oxygenation on cerebral oxygenation and hemodynamics in lambs

To determine the effects of bladderbox alarms during venoarterial extracorporeal membrane oxygenation (va-ECMO) on cerebral oxygenation and hemodynamics, six lambs were prospectively treated with va-ECMO and bladderbox alarms were simulated. Changes …

A Dynamic Objective Evaluation of Peripheral Arterial Disease by Near-Infrared Spectroscopy

Objectives: Near-Infrared Spectroscopy (NIRS), suitable for dynamic measurements, is not routinely used for peripheral arterial disease (PAD). We propose a dynamic NIRS-based measurement to quantify variations in muscle metabolism in PAD. Method: …

Cerebrovascular reserve capacity is impaired in patients with sickle cell disease

Sickle cell disease (SCD) is associated with a high incidence of ischemic stroke. SCD is characterized by hemolytic anemia, resulting in reduced nitric oxide-bioavailability, and by impaired cerebrovascular hemodynamics. Cerebrovascular CO2 …

Emotional modulation of visual cortex activity: A functional near-infrared spectroscopy study

Functional neuroimaging and electroencephalography reveal emotional effects in the early visual cortex. Here, we used functional near-infrared spectroscopy to examine haemodynamic responses evoked by neutral, positive and negative emotional pictures, …

Changes in cerebral oxygenation and hemodynamics during cranial ultrasound in preterm infants

Objectives: To evaluate whether application of a transducer on the anterior fontanelle during cranial ultrasound (US) examination effects cerebral hemodynamics and oxygenation in preterm infants. Study design*: During cranial US examination, changes …

Frontal and motor cortex oxygenation during maximal exercise in normoxia and hypoxia

Reductions in prefrontal oxygenation near maximal exertion may limit exercise performance by impairing executive functions that influence the decision to stop exercising; however, whether deoxygenation also occurs in motor regions that more directly …

A method to calculate arterial and venous saturation from near infrared spectroscopy (NIRS)

For adequate development and functioning of the neonatal brain, sufficient oxygen (O2) should be available. With a fast sampling (fs 50 Hz) continuous wave NIRS device, arterial (SaO2) and venous (SvO2) saturation can be measured using the …

Dynamic topographic mapping of the human bladder during voiding using functional near-infrared spectroscopy

Functional near-infrared spectroscopy (fNIRS) with multichannel instruments and grids of source-detector pairs can map regional change in oxygenation/hemodynamics. Developed for cortical brain mapping, fNIRS technology has relevance in other organs …