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Purpose: To assess the association between skeletal-muscle endurance performance and mitochondrial oxidative capacity of the hamstrings as respectively measured by biomechanical and physiological standards. Methods: Nineteen (12 men and 7 women) …

Abstract Sex differences in near-infrared spectroscopy (NIRS) reactive hyperemia outcomes have been previously reported, with females generally having a lower reperfusion slope. Sex differences have also been reported for adipose tissue thickness …

Purpose This study aimed to investigate the effects of 4-week continuous hypoxic training (CHT) on skeletal muscle oxygenation and hemodynamics, assessed using functional near-infrared spectroscopy (NIRS) and blood oxygenation level-dependent …

Topical capsaicin reduces metaboreflex responses during post-exercise circulatory arrest (PECA) in males, but its effects in females and on microvascular responsiveness in either sex remain unclear. This study hypothesized that capsaicin would reduce …

Purpose The pathogenesis of the long-lasting symptoms which can follow an infection with the SARS-CoV-2 virus (‘long covid’) is not fully understood. The ‘COroNaVirus post-Acute Long-term EffectS: Constructing an evidENCE base’ (CONVALESCENCE) study …

We evaluated whether a short-term cycling intervention in hypoxia, with blood flow restriction, or eccentric cycling induces greater health benefits than traditional cycling in older adults. Fifty-five individuals (68 ± 4 year, 25 females) performed …

Background Erythrocytes are traditionally considered passive oxygen carriers, yet their energetic and redox metabolism plays a critical role in regulating oxygen kinetics. Objective This study integrates experimental and computational data to provide …

Aim Skeletal muscle blood volume responds to the metabolic demands of exercise and augmented microvasculature reactivity. We sought to explore the effects of exercise intensity (maximal vs. submaximal) on near-infrared spectroscopy (NIRS)-derived …

Objective This study investigated the influences of local ischemic preconditioning (LIPC) and remote ischemic preconditioning (RIPC) on muscle deoxygenation before and during a 3-min all-out cycling test (3 MT), as well as on 3 MT performance. …

The present study aimed to investigate which of two commonly performed running interval sessions elicited the greatest magnitude of and time spent with elevated muscle deoxygenation in trained middle-distance runners. Thirteen trained middle-distance …

Purpose: Increasing prevalence of oral contraceptive (OC) use in physically active females highlights the need for sex-specific exercise metabolism research. This pilot study investigated the influence of chronic OC use on the exercising metabolic …

Following an acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a substantial percentage of patients report the persistence of debilitating symptoms, often grouped in a syndrome termed ‘long COVID’. We sought to …

Background Non-invasive determination of mitochondrial capacity via near infrared spectroscopy (NIRS) typically involves voluntary exercise of a single muscle group followed by as many as 26 brief ischemic cuff occlusions to determine a single …

We sought to investigate if critical oxygenation (COx) is a robust marker of exercise intensity, and if it remains stable in normoxia and hypoxia with simultaneous changes in critical power (CP) and heart rate (HR).Thirty-three highly trained …

Introduction Vascular dysfunction is a hallmark of chronic kidney disease (CKD), with previous studies showing progressively deteriorating microvascular reactivity in skeletal muscles with advancing CKD stages. Additionally, cognitive impairment is …

Aims Emerging evidence suggests Type 2 diabetes (T2D) may adversely affect cerebral hemodynamics and oxygenation. This study aimed to explore the impact of uncomplicated T2D on cerebral hemodynamics and oxygenation during maximal exercise. Methods In …

Objective: To investigate the agonist and antagonist muscles implication during a prolonged trunk extension exercise and to determine the relationship with paraspinal muscle metabolic and hemodynamic responses in healthy individuals. Methods: Sixteen …

Purpose: To examine the effect of repeated-sprint training in hypoxia (RSH) on oxygenation kinetics in the vastus lateralis muscle using statistical parametric mapping during repeated treadmill sprints in world-class female Rugby Sevens players. …

This investigation examined a moderate individualized pressure (i.e., percentage of total arterial occlusion pressure [TAOP]) compared to low and high absolute pressures on muscle tissue oxygenation (StO2) throughout ischemic preconditioning (IPC). …

Lower limb exoskeletons have been designed to assist human walking. However, current unpowered exoskeletons primarily targeted the ankle joint, but neglected the energy storage and recoil within the foot. In this study, we proposed an unpowered …