Publications using the PortaLite
Age-related decline in visuo-spatial working memory is reflected by dorsolateral prefrontal activation and cognitive capabilities
Introduction: Visuo-spatial working memory (VSWM) performances undergo a decline throughout aging and are affected by the space in which the task is performed (reaching or navigational). Cerebral oxygenation and cognitive capabilities could explain …
An optical window into brain function in children and adolescents: A systematic review of functional near-infrared spectroscopy studies: fNIRS in developmental cognitive neuroscience
Despite decades of research, our understanding of functional brain development throughout childhood and adolescence remains limited due to the challenges posed by certain neuroimaging modalities. Recently, there has been a growing interest in using …
Cerebral hemodynamic response to a therapeutic bed for procedural pain management in preterm infants in the NICU: a randomized controlled trial
Introduction: We developed a novel device, Calmer, that mimics key components of skin-to-skin holding to reduce stress in preterm infants. Our feasibility trial showed that Calmer worked 50% better than no treatment and no differently from our …
Contact, high-resolution spatial diffuse reflectance imaging system for skin condition diagnosis: a first-in-human clinical trial
Significance: Oxygenation is one of the skin tissue physiological properties to follow for patient care management. Furthermore, long-term monitoring of such parameters is needed at the patient bed as well as outside the hospital. Diffuse reflectance …
Fatigue following COVID-19 infection is not associated with autonomic dysfunction.
BACKGROUND The long-term clinical and physiological consequences of COVID-19 infection remain unclear. While fatigue has emerged as a common symptom following infection, little is known about its links with autonomic dysfunction. SARS-CoV-2 is known …
Hair glucocorticoids and resting-state frontal lobe oxygenation: Findings from The Irish Longitudinal Study on Ageing
Cerebral blood flow and oxygenation are crucial for maintaining healthy brain structure and function, with hypoperfusion and hypometabolism associated with neurodegenerative and neuropsychiatric conditions. Chronic stress and elevated cortisol have …
Intermittent compression of the calf muscle as a countermeasure to protect blood pressure and brain blood flow in upright posture in older adults
Purpose: Orthostatic hypotension, leading to cerebral hypoperfusion, can result in postural instability and falls in older adults. We determined the efficacy of a novel, intermittent pneumatic compression system, applying pressure around the lower …
Influence of cuff-occlusion duration on contrast-enhanced ultrasound assessments of calf muscle microvascular blood flow responsiveness in older adults
New Findings: What is the central question of the study? Cuff-occlusion duration may influence contrast-enhanced ultrasound (CEUS) assessments of skeletal muscle microvascular blood flow responsiveness: what are the effects of 1, 3 and 5 min …
Effect of dark chocolate supplementation on tissue oxygenation, metabolism, and performance in trained cyclists at altitude
Dark chocolate (DC) is high in flavonoids and has been shown to increase nitric oxide in the blood. Increased nitric oxide has the potential to improve delivery of oxygen to muscle, especially in hypoxic conditions, such as altitude. Our aim was to …
A comparison of VȮ2, and muscle and prefrontal cortex tissue oxygen extraction between short and long-term aerobically trained men aged 40-60 years
International Journal of Exercise Science 13(3): 964-978, 2020. This study was designed to compare systemic O2 utilization (VȮ2), and changes in tissue O2 extraction [deoxyhemoglobin ($Δ$HHb)] in the vastus lateralis (VL), gastrocnemius (GAST) and …
A Cross-species Model of Dual-Task Walking in Young and Older Humans and Rats
Introduction: Dual-task walking is common in daily life but becomes more difficult with aging. Little is known about the neurobiological mechanisms affecting competing cognitive demands. Translational studies with human and animal models are needed …
Age and sex differences in frontal lobe cerebral oxygenation in older adults—Normative values using novel, scalable technology: Findings from the Irish Longitudinal Study on Ageing (TILDA)
Aims: Near-infrared spectroscopy (NIRS) is a non-invasive, easy to apply, optical technology for measuring cerebral blood oxygenation, but there is lack of comprehensive population data to aid interpretation and clinical use. Given the importance of …
Altered arterial stiffness, cerebral blood flow and cognitive function in young smokers in response to one-bout of aerobic exercise: Mice vs. hiie
PURPOSE: This study aimed to compare the acute effects of high-intensity interval exercise (HIIE) with moderate-intensity continuous exercise (MICE) on arterial stiffness, cerebral blood flow and cognitive function in young smokers. METHODS: Young …
Associations between Neurocardiovascular Signal Entropy and Physical Frailty
In this cross-sectional study, the relationship between noninvasively measured neurocardiovascular signal entropy and physical frailty was explored in a sample of community-dwelling older adults from The Irish Longitudinal Study on Ageing (TILDA). …
Cardiorespiratory fitness, blood pressure, and cerebral oxygenation during a dual-task in healthy young males
This study aimed to evaluate the effects of cardiorespiratory fitness (CRF) and mean arterial pressure (MAP) on the prefrontal cortex (PFC) oxygenation and dual-task performance in healthy young males. Changes in the concentration of oxygenated …
Comparison of near infrared spectroscopy (NIRS) and near-infrared transillumination-backscattering sounding (NIR-T/BSS) methods
The aim of the study was to compare simultaneously recorded a NIR-T/BSS and NIRS signals from healthy volunteers. NIR-T/BSS is a device which give an ability to non-invasively detect and monitor changes in the subarachnoid space width (SAS). …
Determining whether tennis benefits the updating function in young children: A functional near-infrared spectroscopy study
This study aimed at investigating the behavioral and neuro-electrical impacts of a coordinative exercise intervention on the updating function of the working memory (WM) in young children. Children in the experimental group was tested on the 1-back …
Dopaminergic therapy and prefrontal activation during walking in individuals with Parkinson's disease: does the levodopa overdose hypothesis extend to gait?
The “levodopa-overdose hypothesis” posits that dopaminergic replacement therapy (1) increases performance on tasks that depend on the nigrostriatal-pathway (e.g., motor-control circuits), yet (2) decreases performance on tasks that depend upon the …
Dynamic cerebral autoregulation estimates derived from near infrared spectroscopy and transcranial Doppler are similar after correction for transit time and blood flow and blood volume oscillations
We analysed mean arterial blood pressure, cerebral blood flow velocity, oxygenated haemoglobin and deoxygenated haemoglobin signals to estimate dynamic cerebral autoregulation. We compared macrovascular (mean arterial blood pressure-cerebral blood …