Hypoxia and Altitude studies
Last updated on
2022-09-07
A constant supply of oxygen to our muscles and organs is essential for the maintenance of proper body functioning. However, we frequently encounter conditions where the oxygen demand by tissue exceeds the supply, thereby leading to a state of oxygen deprivation, also called hypoxia. Because of our constant need for oxygen, our body has developed multiple mechanisms that detect oxygen levels, which in turn can activate appropriate responses to counter hypoxia and generate a higher oxygen supply. Moreover, understanding the physiological mechanism underlying the bodily response to oxygen deprivation is of major importance and our NIRS devices have shown to be a great tool in this field of research.
Publications
Adding a sustained attention task to a physically demanding cycling exercise exacerbates neuromuscular fatigue and impairs cognitive performance in both normoxia and hypoxia
Purpose Both cognitive motor dual-tasks (CMDT) protocols and hypoxic environments have been associated with significant impairments in …
Differences in cerebral oxygenation during exercise in patients with idiopathic pulmonary fibrosis with and without exertional hypoxemia: does exercise intensity matter?
Introduction and Objectives Patients with idiopathic pulmonary fibrosis (IPF) present respiratory derangements at rest and during …
Muscle Oxygen Delivery in the Forearm and in the Vastus Lateralis Muscles in Response to Resistance Exercise: A Comparison Between Nepalese Porters and Italian Trekkers
Altitude ascending represents an intriguing experimental model reproducing physiological and pathophysiological conditions sharing …
Oral nitrate supplementation differentially modulates cerebral artery blood velocity and prefrontal tissue oxygenation during 15 km time-trial cycling in normoxia but not in hypoxia
Background: Nitrate is a precursor of nitric oxide (NO), an important regulator of cerebral perfusion in normoxic and hypoxic …
High-intensity Interval training enhances mobilization/functionality of endothelial progenitor cells and depressed shedding of vascular endothelial cells undergoing hypoxia
Purpose: Exercise training improves endothelium-dependent vasodilation, whereas hypoxic stress causes vascular endothelial dysfunction. …
Effect of end-tidal CO 2 clamping on cerebrovascular function, oxygenation, and performance during 15-km time trial cycling in severe normobaric hypoxia: the role of cerebral O 2 delivery
During heavy exercise, hyperventilation-induced hypocapnia leads to cerebral vasoconstriction, resulting in a reduction in cerebral …